Zhejiang Dongjian Pharmaceutical Co., Ltd

CDMO Service

Assessment phase
Laboratory Development
Laboratory Validation

Patent research 

Literature assessment 

Proposals of potential synthesis routes


IP verification of proposed synthesis routes 

Raw materials/intermediates market availability evaluation 

Cost calculation

Batch Record&Manufacturing

Laboratory verification of synthesis routes 

Selection of synthesis route for optimization or based on IP assessment and cost calculation 

Development of purification method 

Preliminary analytical methods development

Optimization of chosen synthesis route- technology development 

Development of analytical methods for product 

Process laboratory validation 

Validation of analytical methods 

Transfer of analytical methods to Quality Control Laboratory 

Cost calculation and IP assessment

Transfer to Manufactory 

Scaling up in Pilot Plant 

Scaling up in factory 

Documenting in the batch production records, the facility log, or other documentation system 

IP control and project confidentiality.

Meeting customer expectations

DongjianPharma brings many years of experience in the Small Molecule (Including intermediates)development and manufacturing market, where we have considerable experience with a repertoire of chemical reactions and transformations, including but not limited to:

Chemical reactions and transformations

>> Hydrogenations 

>> Oxidations 

>> Cryogenics 

>> Friedal-Crafts 

>> Organometallics 

>> Amination 

>> Cyanation

>> Carbonylation 

>> Diels-Alder 

>> Acylation 

>> Phosphorylation 

>> Bio-Catalysis 

>> Chiral Synthesis 

>> Halogenation reaction

>>Being active Project Team Member 


>>Adequate experience and resource availability

>>Equipped facility

>>ICH guidelines Q11 (Development and Manufacture of Drug Substances) and Q9 (Quality Risk Management) compliance 

>>Good Laboratory Practice (GLP) 

>>Good Manufacturing Practice (GMP) 

>>Strictest compliance with Intellectual Property Management